Extended Data Fig. 8: Mono-methylation of R293 in TDP-43 filaments from type A FTLD-TDP.
From: TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
Mass spectra of TDP-43 peptides containing mono-methylated R293 from TDP-43 filaments isolated from the prefrontal cortex of individuals 1 and 2. Such peptides were not detected for individuals 3–5, possibly because fewer total peptides containing R293 of TDP-43 were detected for these individuals compared to individuals 1 and 2.
