Extended Data Fig. 7: Organization of the mtDNA non-coding region.
From: Nuclear genetic control of mtDNA copy number and heteroplasmy in humans
Colors indicate annotation type. Yellow, rRNA gene; steel, tRNA gene; purple, coding genes; green, non-coding region (also referred to as the control region); midnight, conserved sequence boxes (CSB); salmon stripe pattern, hyper-variable regions (HVR). The mtDNA D-loop refers to the region within the non-coding region often showing triple-stranded DNA due to the persistence of the 7S DNA. Annotations are oriented with the rCRS reference genome.
