Extended Data Fig. 10: Brain concentration of ketamine after a single i.p. injection of 5 mg kg−1 ketamine in CRS mice, as measured by LC-MS/MS.
From: Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb
As noted by the dotted line, the half-life of ketamine is 13 min. Error bars indicate SEMs. (see Supplementary Table 1 for statistical analyses and n numbers).
