Fig. 5: Earliest detection of structural fetal brain hemispheric asymmetries.
From: Normative spatiotemporal fetal brain maturation with satisfactory development at 2 years
a, 3D reconstructions at 14, 21 and 24 weeks’ gestation with the log-Jacobian maps overlayed on the US atlas template. Blue indicates regions where the left hemisphere is larger than the right (L > R; pink arrows) and vice versa (R > L). b, Physical configuration of the fetal ChP, shown at 4 week intervals starting from 14 weeks’ gestation. Average ChP shape for the left (blue) and right (orange) hemispheres are shown separately. c, Normalized ChPV, highlighting the rate of ChP shrinkage relative to TBV. d, Visual summary of the population average of cortical asymmetries. Colours indicate the gestational age at which asymmetry was first detected. Dashed lines indicate Broca’s and Wernicke’s areas. The parcellation-based results do not apply before 18 weeks’ gestation.
