Extended Data Fig. 8: Spike-frequency adaptation in pIP10 neurons (supplement to Fig. 5).
From: Flexible circuit mechanisms for context-dependent song sequencing
a, In vivo patch-clamp electrophysiology of descending neuron pIP10. Action potentials (spikes) were observed both during injection of positive current and following injection of negative current (post-inhibitory rebound spikes). b, For each current stimulus amplitude, instantaneous spike rates were defined as the inverse of each inter-spike interval for all successive pairs of spikes observed within the trial. Shown is the median (per stimulus) instantaneous spike rate following negative or during positive current injection. c, Instantaneous spike rate of the first ten spike pairs in each trial, normalized by the spike rate of the first pair. Normalized spike rate decreases for successive spikes, indicative of spike-frequency adaptation.
