Extended Data Fig. 2: Dorsoventral and appendage patterning in Patiria miniate.
From: Molecular evidence of anteroposterior patterning in adult echinoderms
a, Schematic representation of D–V patterning in bilaterians. b, Expression profile of D–V specification and patterning genes along the P–D, O–A and M–L dimensions of the RNA tomography. For the M–L dimension, the dotted line indicates the midline. c-v,y-α, HCRs of P. miniata brachiolariae (c,h,m), early metamorphosis (d,i,n), late metamorphosis (e,j,o) and postmetamorphic juveniles (f,g,k,l,p-v,y-α) imaged from the oral side. In c-q,t,u,y-α, specimens are counterstained with DAPI (blue). g,l,q,r,s,v, Magnification of a single ambulacrum. c-v, Expression patterns of genes involved in D–V axis specification and patterning. w, Schematic representation of limb proximodistal patterning in bilaterians. x, Expression profile of limb proximodistal patterning genes along the P–D dimension of the RNA tomography. y-α, Expression patterns of genes involved in limb proximodistal patterning. Scale bars, 100 µm.
