Extended Data Fig. 9: Comparing SARS-CoV-2 infection between hACE2 mice and golden hamster.
From: Mouse genome rewriting and tailoring of three important disease loci
(a) Schematic of the longitudinal SARS-CoV-2 infection experiment for 116 kb mice and wild-type golden hamsters. (b-c) RT-qPCR analysis of SARS-CoV-2 nucleocapsid gene in lung (b) and trachea (c) of 116 kb mice and hamsters. hACE2 mice, n = 5 (5 dpi), 4 (14 dpi). Hamsters, n = 5 (5 dpi), 5 (14 dpi). SARS-CoV-2 RNA level was normalized Actb and to uninfected control. Bars represent mean ± SEM of biological replicates.
