Fig. 5: Mechanistic comparison of group II introns and the spliceosome.
From: Structural insights into intron catalysis and dynamics during splicing
a, Comparison of the overall fold of group IIC introns (top) and the aligned active sites of the Oceanobacillus iheyensis intron before hydrolysis (nucleophilic water in light blue) and the E. rectale intron before branching (bpA in dark red) (bottom). b,c, Conserved RNP interface and branch helix dynamics in group II RNPs (b) and spliceosomes (c) during the first- to second-step transition.
