Extended Data Fig. 12: Histograms of the counts of the network motifs in each subclass’s gene regulation network (GRN) grouped by main class (a) or regions (b).

The names of the network motifs are the same ones in Extended Data Fig. 11d. Only the class with at least 3 subclasses were shown here. For each histogram, we added the corresponding density plot. The telencephalon region includes isocortex, olfactory bulb, hippocampus, striatum, pallidum, and amygdala; the diencephalon region includes thalamus and hypothalamus; the hindbrain includes pons and medulla. c, Normalized signals of Atf3 ChIP-seq at Klf4 in bone marrow-derived macrophages (BMM) showing Klf4 is likely to be a putative target of Atf3. d, Normalized signals of Atf3 ChIP-seq at Tal1 in bone marrow-derived macrophages (BMM) showing Tal1 is likely to be a putative target of Atf3.