Extended Data Fig. 6: Results corresponding to testing AF-Cluster for other proteins.
From: Predicting multiple conformations via sequence clustering and AlphaFold2
a) Predicting the structure of RfaH in AF2 with the complete MSA from ColabFold34 returns the autoinhibited state with a mean plDDT of 68.6 (note low confidence in the first alpha-helix of the CTD.) b) B-factors of PDB 5OND58, indicating that the last helical turn of the second to last helix has high B-factors (arrow). C) AF-Cluster only predicts the monomeric state for proteins that switch between monomeric and oligomeric states.
