Extended Data Fig. 4: The sequences, models, and cryo-EM densities of the RNA templates.
From: Structures of the promoter-bound respiratory syncytial virus polymerase
(a) The sequences, models, and cryo-EM densities of leader promoter Le10 (the position 3 pre-initiation state). The electron density maps of Le10 were shown at the contour levels of 2.5 and 1.5 σ. Detailed electron density maps for Le10-T1U (1.5 σ), Le10-T2G (1.5 σ), Le10-T4G (2.5 σ), and Le10-T10U (2.5 σ) were also shown. (b) The sequences, models, and cryo-EM densities of trailer complementary promoter TrC10 (the position 1 pre-initiation state.) The electron density map of TrC10 was shown at the contour levels of 2.5 σ. Detailed electron density maps for TrC10-T2G (2.5 σ) and TrC10-T8U (2.5 σ) were also shown. The residue is denoted by the template (T) position number with the base name. Note that the 5'ends of the visible RNA residues Le10-T10U (the ending hydroxyl group) and TrC10-T8U (the internal phosphate group) are different, confirming the difference between the modelings of Le10 and TrC10.
