Extended Data Table 3 A. baumannii isolates, including their phenotypic and MLST profile, selected for use in in vitro and in vivo studies

From: A novel antibiotic class targeting the lipopolysaccharide transporter

  1. MIC broth microdilution conducted in CAMHB for tigecycline (TGC), colistin (CST), meropenem (MEM), RO7075573, and zosurabalpin (ZAB), and in CAMHB with 20% human serum (HS) for ZAB*. RO7075573 and ZAB endpoint MIC value in CAMHB read at 80% of bacterial growth inhibition due to observed trailing effect. MIC values represent the mode of ≥3 replicates, with the following exceptions: for ATCC 17978, the MIC value of 1 replicate is reported for RO7075573; for isolates ROB08701, ROB08702, ROB08704, ROB08707, ROB08709, ROB08710, the MIC value of 1 replicate is reported for TGC, CST, MEM and ZAB. MLST, multilocus sequence typing; n/a, not assessed; NF, Not Found (MLST could not be determined because one housekeeping gene necessary for MLST classification was not identified in this isolate). a from ATCC; b from LGC; c from Aptuit; d from CDC.
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