Fig. 4: Phenome-wide associations of the Duffy blood group locus (rs2814778, ACKR1). | Nature

Fig. 4: Phenome-wide associations of the Duffy blood group locus (rs2814778, ACKR1).

From: Genomic data in the All of Us Research Program

Fig. 4: Phenome-wide associations of the Duffy blood group locus ( rs2814778 , ACKR1).

Results of genetic-ancestry-stratified phenome-wide association analysis among unrelated individuals highlighting ancestry-specific disease associations across the four most common genetic ancestries of participant. Bonferroni-adjusted phenome-wide significance threshold (<2.88 × 10−5) is plotted as a red horizontal line. AFR (n = 34,037, minor allele fraction (MAF) 0.82); AMR (n = 28,901, MAF 0.10); EAS (n = 32,55, MAF 0.003); EUR (n = 101,613, MAF 0.007).

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