Extended Data Fig. 8: No change in excitability of aVMHvlOXTR cells one day after defeat. | Nature

Extended Data Fig. 8: No change in excitability of aVMHvlOXTR cells one day after defeat.

From: A dedicated hypothalamic oxytocin circuit controls aversive social learning

Extended Data Fig. 8

a. Representative recording traces of aVMHvlOXTR cells under specific current steps, ranging from 50 pA to 250 pA, from single-housed (SH), defeated (D) and socially interacted (SI) male mice. b. Frequency-current (F-I) curve of aVMHvlOXTR cells in SH, D, and SI groups. Two-way repeated measure ANOVA with Sidak’s multiple comparison test. *p < 0.05 for D vs. SI comparisons. If not indicated, p > 0.05. c. Resting Membrane Potential (RMP) of aVMHvlOXTR cells in SH, D, and SI groups. d. Rheobase of aVMHvlOXTR cells in SH, D, and SI groups. e. Input resistance of aVMHvlOXTR cells in SH, D, and SI groups. Plots with error bars represent mean±s.e.m. Circles in c-e represent individual recording cells. Numbers on the plots indicate the number of cells. Cells are from 3-4 male mice per group. One-way ANOVA with Tukey’s multiple comparisons test (c) and Kruskal-Wallis test with Dunn’s multiple comparisons test (d-e). All statistical tests are two-tailed. See Supplementary Table 1 for detailed statistics.

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