Extended Data Fig. 1: Calibrated 14C-dating curves of samples used for ancient genome reconstruction and damage profiles for aDNA authentication.
From: Redefining the treponemal history through pre-Columbian genomes from Brazil
Calibration conducted by Calib radiocarbon calibration program, showing the a) pre- and b) post-reservoir effect corrected (modelled) curves for the four samples (ZH1390, ZH1540, ZH141 and ZH1557) included in the genomic analyses. Damage profiles obtained with the DamageProfiler tool130 show the misincorporation patterns induced by age, for each sample that yielded a reconstructed genome: c) ZH1540, d) ZH1390, e) ZH1541 and f) ZH1557. A pattern of cytosine-to-thymine base misincorporation accumulating at the end of the reads is indicative of authentic ancient DNA in the sample.
