Extended Data Fig. 7: Single-cell- and population-level representations of prosocial behaviors and different states of demonstrators.
From: Cortical regulation of helping behaviour towards others in pain
(a) Schematics illustrating dissociable and shared aspects in the neural representations of different states or behaviors at the single-cell and population levels. (b-j) Decoding performance using all cells and after removing significantly responsive cells in different groups of decoding analysis. Data in the “All cells” groups in (b-j) are the same as presented in Figs. 3h, 3p, 3s (left), 3t (left), 5e, 5 l, 5p, 5 m, and Extended Data Fig. 8n, respectively. (k, l) Fraction of variance explained by the first three PC (k) and PLS (l) components in the data used for decoding of others’ neutral versus pain state (Fig. 3h). In (b-l), the center line in the boxplots indicates the median, the box limits indicate the upper and lower quartiles, and the whiskers indicate the minimum and maximum values (b-j) or data within 1.5× interquartile range (k, l). n = 11 mice in (b, h, j-l), 6 mice in (c-e, g), 8 mice in (f), 12 mice in (i). (b-j) Two-sided Wilcoxon signed-rank test. ***P < 0.001, **P < 0.01, *P < 0.05. ns, not significant. Details of statistical analyses are provided in Supplementary Table 1.
