Fig. 6: Designed train track fibres. | Nature

Fig. 6: Designed train track fibres.

From: Blueprinting extendable nanomaterials with standardized protein blocks

Fig. 6: Designed train track fibres.

a, Components of the train track designs: a branch module, a split module and a C2 interface module. b, Train track designs. The asymmetric unit is outlined in the top left design; red and blue are unique protein chains. Taking advantage of the extensibility of the building blocks, four different train track designs were created, starting with the design at the top left. Top right: increasing the spacing between rungs by expanding the split module. Bottom left, increasing the length of the rungs by expanding the C2 module. Bottom right: increasing both rung spacing and length by expanding both the split and C2 modules. Inserted segments are in yellow. c, An ns-EM micrograph of the design at the top left of b. Scale bar, 25 nm. d, ns-EM 2D class averages of the four designs in b, shown in the same overall layout. The design models are overlaid on the class averages at 1:1 scale. Scale bar, 25 nm.

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