Extended Data Fig. 3: Quality controls of MPAS results.
From: Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain
(a-b) Violin plot distribution of log-transformed total read depths (y-axes) of individual variant positions in 321 or 147 samples from ID01 or ID05 (x-axes), respectively. The blue dashed lines indicate 1000× read depth. (c-d) Correlation between sqrt-t AF of individual variants from WGS and MPAS. Error bars of individual points: square-root-transformed lower and upper bounds for binomial distribution of individual AFs. Blue horizontal dashed lines: Lower bound for binomial distribution detection threshold. r and p-values (two-tailed) from Pearson’s Product-Moment correlation. Identity lines (red).
