Extended Data Fig. 8: Wnt5a overexpression promotes cell proliferation in mouse skin.
From: Emx2 underlies the development and evolution of marsupial gliding membranes
Induction of Wnt5a in postnatal day 37 laboratory mice results in a significant increase in cellular proliferation, as measured by EdU incorporation (Mean + SE). Shown are comparisons between double transgenic (R26rtTAHET;tetO-Wnt5aHET) and control littermates R26rtTAHET;wt/wt. Statistical significance (N = 4; P = 5.9 × 10−5) was assessed using a general mixed effects model one-way ANOVA test. Dotted line delineates the dermis-epidermis boundary. Scale bars: 100 µm.
