Extended Data Fig. 8: Observed heteroplasmy in ancestral lineages.
From: Single-cell analysis reveals context-dependent, cell-level selection of mtDNA
a-b, Heteroplasmy levels in all 720 ancestral lineage with cells detected at both days (a), and a random subsample of 100 of those lineages (b), in LHON-edited and SILENT-edited populations at day 0 and day 5. Each line segment represents a unique ancestral lineage and connects that lineage’s mean heteroplasmy at day 0 with that of day 5.
