Extended Data Fig. 9: Representative images of mutant and total KRAS RNA ISH staining in histologically normal ductal epithelial cells adjacent to PanIN.
From: 3D genomic mapping reveals multifocality of human pancreatic precancers
A. KRAS G12R mutant RNA ISH probe staining (red puncta) in a PanIN and adjacent normal ductal cells, with consecutive H&E-stained tissue section. B. Universal KRAS reference ISH probe staining of same PanIN and adjacent normal ductal cells, with corresponding H&E image. Scale bars = 50 µm.
