Fig. 6: IS110 subfamilies encode distinct and diverse bridge RNA secondary structures in different non-coding end sequences. | Nature

Fig. 6: IS110 subfamilies encode distinct and diverse bridge RNA secondary structures in different non-coding end sequences.

From: Bridge RNAs direct programmable recombination of target and donor DNA

Fig. 6: IS110 subfamilies encode distinct and diverse bridge RNA secondary structures in different non-coding end sequences.

a, Non-coding end length distribution for IS110 and IS1111 group elements. Box plots show median (centre line), IQR (box edges) and 1.5 × IQR (whiskers). b, Location of predicted bridge RNA for IS110 and IS1111 group elements. c, Phylogenetic tree of the 274 IS110 recombinases catalogued by ISfinder. d, Bridge RNA consensus structures from six diverse IS110 elements. Secondary structures are shown with internal loops coloured according to the sequence that they complement: target (blue), donor (orange) or core (green).

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