Extended Data Fig. 9: Population dynamics before and after OVX in the same female.
From: Encoding of female mating dynamics by a hypothalamic line attractor
(a, b,) Neural raster and behaviors and rSLDS model performance (measured as forward simulation error, see Methods) for one example mouse in receptive day of natural estrus cycle a, and same mouse on hormone primed day after OVX (day3, oil + E | P) b. (c, d), Integration dimension identified by rSLDS on natural cycle receptive day c, and during hormone primed day after OVX d. (e, f), Flow field e, and neural trajectories of dynamical system f, with line attractor highlighted of model fit during the receptive state of the estrus cycle. (g, h), Same as e, f, for model fit during hormone primed day after OVX. i, Dynamics of integration dimension discovered during natural cycle receptive day compared to activity of the same dimension on unreceptive days. j, Dynamics of integration dimension in the same mouse discovered during hormone primed day (day 3) compared to the activity of the same dimension during non-primed days. (k, l), Neural raster and behaviors and rSLDS model performance for mouse in proestrus day of natural estrus cycle k, and same mouse on hormone primed day after OVX (day3, oil + E | P) l. m, Principal components of mouse dynamic system fit during hormone primed day. (n, o), Flow field n, and neural trajectories of dynamical system. o, with line attractor highlighted of model fit during the hormone primed day after OVX in mouse.
