Fig. 2: Tissue contractility modulates GDF1 expression in intact epiblasts.
From: Self-organized tissue mechanics underlie embryonic regulation
a–f, Tissue deformation maps (a,e,i,m), time evolution of strain rates along the margin (b,f,j,n; 0 mm is posterior) and corresponding expression of GDF1 (c,g,k,o) and BRA (d,h,l,p) in control (a–d; n = 32), calyculin-A-treated (e–h; n = 18), H1152-treated (i–l; n = 13) and Ski-1-treated (m–p; n = 6) biologically independent embryos. Colours in a, b, e, f, i, j, m and n quantify contraction (red) and expansion (blue). Scale bars, 1 mm (a, c, d, e, g, h, i, k, l, m, o and p).
