Fig. 1: Modular robotic workflow and heuristic reaction planner.
From: Autonomous mobile robots for exploratory synthetic chemistry
a, Workflow design for autonomous synthesis using mobile robots for sample transport and handling between the ISynth synthesizer and the MS and NMR analysis stations. b, An application-agnostic heuristic reaction planner takes input from the MS and NMR measurements and combines these two orthogonal datasets to plan the next stage in the synthesis experiment. Only reactions that pass predetermined, application-specific thresholds for both the MS and the NMR measurements are deemed to be hits, which are then taken forward for scale-up or for further reproducibility tests (green, pass; orange, fail).
