Extended Data Fig. 10: Circuit diagram of aIPg modulation of visual processing.
From: Social state alters vision using three circuit mechanisms in Drosophila
A detailed circuit map of the mechanisms detailed in Fig. 1b. This diagram shows additional downstream targets of aIPg including those involved in regulating information flow from LC9 and LC11. The diagram also illustrates that CL053, PVLP114, AOTU015 and AOTU023 are each upstream of descending interneurons (DNs) that traverse the neck into the ventral nerve cord where they likely regulate motor action. Each of these neurons connect to largely non-overlapping sets of DNs51,84,85, implying that these parallel pathways control different motor actions. Cell numbers are listed under cell type name and the number of synapses between cell types are listed on the arrows. Numbers within arrows indicate synapses numbers. The top six downstream targets of aIPg are represented in this diagram: (1) PVLP114; (2) IB112; (3) SMP054; (4) SIP017; (5) CL053; and (6) AOTU015. In the male OL53, Li22 devotes about 40% of its output synapses to LC10-group cell types and provides input to all LC10-group cell types. On average, the number of Li22 inputs to individual cells in each of the LC10-group cell types are as follows: LC10a, 23; LC10b, 12; LC10c, 27; LC10d, 32; LC10e, 4; and LoVP76/LC10f, 0 in males and LC10a, 8; LC10b, 6; LC10c, 14; LC10d, 15; LC10e, 1.4 and LC10f 1.5 in females. Synapse counts shown are from hemibrain data except IB112 to Li22 and Li22 to LC10s, which were from FlyWire.
