Extended Data Fig. 8: CNVs in the re-sequenced database of wheat and its tetraploid ancestors indicated VRN-A1 gene experienced strong selection in wheat origin, spread and breeding in reaction to the environments.
From: Pan-genome bridges wheat structural variations with habitat and breeding

a-b, Hapmap of VRN-A1 copy number in landrace and cultivar. Blue represents VRN-A1 gene loss (0 copy), green, orange, and red represent VRN-A1 being 1 to 3 copies respectively. During the spread of wheat to China, the copy number increased (triple copy proportion increased), and the share of triple copy types of VRN-A1 significantly increased in the colder north-western region. However, in modern cultivars the frequency of cultivars with one or two copies increased in north China, probably caused by temperature global warming. The sizes of pies are relative to the count of samples in each location. c, Mean temperature in January from 1961 to 2020 in Henan, the largest wheat production province in China. The average temperature in January from 1981 to 2020 is marked with an orange line.