Extended Data Fig. 4: Leukaemia induction and observation in mice.
From: Fetal hepatocytes protect the HSPC genome via fetuin-A
a, Experimental design for leukaemia induction and monitoring in mice. ENU, N-ethyl-N-nitrosourea; PB, peripheral blood; BM, bone marrow. b, c, The physical symptoms of leukaemic and normal control mice. d, Spleens and lymph nodes from leukaemic and control mice. b-d, Control, n = 5, Leukaemic, n = 51. e, The proportion of lineage-negative cells in the BM of leukaemic and control mice (Control, n = 5, Leukaemic, n = 51; mean ± s.d.). f, Representative H&E images of tissue sections (Control, n = 4; Leukaemic, n = 10). Scale bars, 100 and 25 μm. The n represents individual mice. Statistical tests: unpaired two-sided Student’s t-test (e).
