Extended Data Table 1 Antiviral activity of JNJ-9676 against different coronaviruses

From: A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein

  1. CC50, 50% cytotoxic concentration; CoV, coronavirus; ECx, x% effective concentration; IBV, infectious bronchitis virus; IQR, interquartile range; MERS-CoV, Middle East respiratory syndrome coronavirus; MHV, mouse hepatitis virus; N, number of independent technical repeats; NA, not available; PDCoV, porcine deltacoronavirus; SARS-CoV, severe acute respiratory syndrome coronavirus.
  2. For N = 2, no IQR could be calculated. For N = 1, no median nor IQR could be calculated.
  3. aIn one experiment the EC90 could be calculated, in other experiments HCoV-OC43 inhibition did not reach 100%, the EC50 value is a relative EC50, the EC50 value is a relative EC50.
  4. bMERS-CoV inhibition did not reach 100%, median EC90 values could not be calculated, the EC50 value is a relative EC50.
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