Extended Data Fig. 9: Germ-free mice have impaired germinal centre formation following vaccination with the PCV13 vaccine. | Nature

Extended Data Fig. 9: Germ-free mice have impaired germinal centre formation following vaccination with the PCV13 vaccine.

From: Bifidobacteria support optimal infant vaccine responses

Extended Data Fig. 9

Confocal microscopy of dLNs collected from mock (PBS) and PCV13 vaccinated GF and SPF mice that were vaccinated at day 28 of life with one 3 μg dose of PCV13 vaccine i.p. Data shown are at two weeks post-immunisation. CD3, CD21/35, GL7 and IgD staining are visualised separately and then merged. A white box has been placed around the GL7 staining, which visible only in the vaccinated SPF mice. Data are from a single experiment. The scale bar represents 100 μm.

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