Extended Data Fig. 11: Performance of various functional metrics in predicting axon-dendrite co-travel distance (L_d, Axonal scale) or synapse density (N_syn/mmL_d, Synaptic scale).

Model performance of GLMMs (Nakagawa’s conditional R²) for predicting axon-dendrite co-travel distance (L_d): a, b, c and synapse density (N_syn/mmL_d): d, e, f, for all coregistered neurons: a, d, all visually responsive, well predicted neurons: b, e, and neurons tuned to oriented stimuli: c, f. The GLMMs are fit to predict axon-dendrite co-travel distance or synapse density independently with each functional metric, the projection type, and the interaction between the two while considering the interaction term of projection type and presynaptic neuron identity as random effects. The baseline models were not fitted with information about functional metrics. They predict axon-dendrite co-travel distance or synapse density with the projection type alone while considering the interaction term of projection type and presynaptic neuron identity as random effects.