Extended Data Fig. 8: CM05 analysis in the spleen.
From: Cross-tissue multicellular coordination and its rewiring in cancer
(a) Venn diagrams showing the overlap of four CM05 subsets in all signature genes (left) and signature TFs (right). (b) Expression of NR4A1, NR4A2, and NR4A3 in CM05 subsets and other cells within the same cell types. (c) Venn diagram showing the overlap of regulon TFs identified by SCENIC analysis and signature TFs. The eight shared TFs (key regulators) and other signature TFs are indicated. (d) Regulatory network of 17 convergent regulons in CM05. The key regulators are highlighted. Regulatory relationships are determined by SCENIC analysis. (e) Venn diagrams showing the overlap in regulon targets among different cell types. Hypergeometric tests. TF, transcription factor.
