Extended Data Fig. 5: Pauses in firing of optogenetically activated SNr neurons align with behaviour.

a-d, Single trial raster plots (top) and average firing rate with standard error of the mean (bottom) of single SNr neurons aligned to cue presentation (left) and lever press (right) on control (top, grey in average) and laser trials (bottom, blue in average) in which a press was executed within a 1.5 s interval after the cue. Note for all neurons increase in spike rate over baseline upon laser exposure (left; note the variability in single neuron responses to the optogenetic perturbation, despite the overall transient effect at the population level shown in Fig. 4d) followed by a pause in both control and laser trials aligned to lever press (right). Light blue boxes indicates periods of laser application.