Extended Data Fig. 7: Identification of in vivo connected pairs between SNr and midbrain.
From: Dynamic basal ganglia output signals license and suppress forelimb movements
a, Allen CCF registered location of the neurons recorded in the Midbrain along the rostro-caudal levels (displayed at 100 micrometre intervals) of the midbrain reticular nucleus (MRN) and superior colliculus (SC), here referred to as midbrain for simplicity. b, Z-scored cross-correlogram of the 8 identified putatively connected SNr to Midbrain neuron pairs showing cross-correlation of spike times between pre and postsynaptic neuron with minimum cross-correlation at less than 2 ms, showing strong inhibition of the postsynaptic Midbrain neuron by spikes of the presynaptic SNr neuron as a feature of all identified pairs. c, Respective locations of the presynaptic SNr neuron and postsynaptic Midbrain neuron for each of the 8 identified connected pairs. Note the resemblance of the locations of the Midbrain neurons to the location of the synaptic terminals from the latRM projecting SNr neurons in the midbrain shown in Extended Data Fig. 6.
