Extended Data Fig. 10: Ku binds to SINEs without selective preference for a specific Alu subfamily.
From: Ku limits RNA-induced innate immunity to allow Alu expansion in primates
a-b, Two other nuclear RBPs are shown to compare to Ku and DNA-PKcs, highlighting the strong preference for introns and repetitive elements for Ku and DNA-PKcs. c-d, The genomic distribution of DNA-PKcs irCLIP tags (c) and overlap with repetitive elements (d). e-f, as Alu elements of specific subfamilies with the numbers overlapping with Ku (e) and DNA-PKcs (f) irCLIP peaks shown in the y-axis and the total numbers in the human genome shown in the x-axis. The red arrows indicate Alu subfamilies with lower-than-expected irCLIP signal.
