Extended Data Fig. 7: Community composition influences the growth of various Gammaproteobacteria pathogens.
From: Non-antibiotics disrupt colonization resistance against enteropathogens
a) Growth of K. pneumoniae, S. flexneri, Y. enterocolitica and E. coli in 19-member communities (each missing the species indicated in the y-axis) compared to untreated Com20. Red vertical and horizontal lines represent the mean ± 1 s.e.m. across three biological replicates. P values from two-tailed t-tests; only values ≤ 0.05 are shown. b,c) Metabolic competition b) and complementarity indices c) of pathogenic Gammaproteobacteria species, calculated from genome-scale metabolic models (see Methods). Dashed horizontal lines indicate the mean levels of S. Tm with members of Com21. Red points and bars represent mean ± 1 s.e.m. d,e) Distribution of competition d) and complementarity c) index values of each member of Com21 against all other members of the community and against S. Tm are shown by the boxplots (n = 21 other species per boxplot). The exact values of the indices against E. coli and S. Tm are indicated by black and orange diamonds, respectively. Note that the indices are not symmetric. In b-e) boxplots show the median, IQR, whiskers to the min/max within 1.5 IQR, and outliers as individual points.
