Extended Data Fig. 9: Multivariate cluster join counts analysis.
From: Pathology-oriented multiplexing enables integrative disease mapping
(a) Schematic representation of our approach to characterize direct spatial interactions between neighbouring clusters. (b) Spatial interactions highlight changes in associations across disease states and scales. GR, Glucocorticoid receptor; PTMs, Post-translational modifications; PTs, proximal tubular cells; DT, distal tubule; CD, collecting duct; ER, Endoplasmic reticulum; MVs, microvesicles; ECM, Extra cellular matrix; activ, activation; podo, podocytes; physio, physiology; metab, metabolism; cytoskel, cytoskeletal; ECs, endothelial cells; GECs, glomerular endothelial cells; mTOR, mammalian target of Rapamycin; macro, macrophages; lyso, lysosomes; microtub, microtubules; mechanotrans, mechanotransduction; Cell adh, cell adhesion; Myofib, myofibroblasts.
