Extended Data Fig. 2: Olfactory bulb GABAergic and immature neuronal cell types.

(a) UMAP representation of OB GABAergic and immature neuronal types, coloured and labelled by supertype. (b) Constellation plot of OB-IMN GABA clusters using UMAP coordinates shown in a. Nodes are clusters coloured by supertype and grouped in bubbles by subclass. (c) Dendrogram of OB-IMN GABA supertypes followed by bar graphs showing major neurotransmitter type and region distribution of profiled cells, followed by dot plot showing marker gene expression in each supertype from the 10xv3 dataset. Dot size and colour indicate proportion of expressing cells and average expression level in each supertype, respectively. (d) Schematic drawing of anatomical structure in MOB (left) and AOB (right). Abbreviations: RMS, rostral migratory stream; GrO, granular layer; IPl, internal plexiform layer; Mi, mitral layer; EPl, external plexiform layer; Gl, glomerular layer. (e-k) Representative MERFISH sections showing the location of OB subclasses 39 OB Meis2 Thsd7bGaba (e), 40 OB Trdn Gaba (f), 42 OB-out Frmd7 Gaba (g), 43 OB-mi Frmd7 Gaba (h), 44 OB Dopa-Gaba (i), 41OB-in Frmd7 Gaba (j), and 45 OB-STR-CTX Inh IMN (k). Cells are coloured and labelled by supertype. Triangular schematic denotes the most granular hierarchical level shown in the panels (ST: supertype).