Extended Data Fig. 7: SPFpPth2 neurons promote the initiation of consummatory behaviors in an ongoing mating interaction. | Nature

Extended Data Fig. 7: SPFpPth2 neurons promote the initiation of consummatory behaviors in an ongoing mating interaction.

From: A circuit that integrates drive state and social contact to gate mating

Extended Data Fig. 7: SPFpPth2 neurons promote the initiation of consummatory behaviors in an ongoing mating interaction.

a, Experimental design (top) and example behavior raster (bottom) for randomized stimulation or sham trials with an intact female (i.e. open-loop). b-e, Reaching (top) and mounting (bottom) during randomized optogenetic stimulation or sham trials. (b) Total duration. (c) Incidence, percent of trials. (d) Frequency, number of bouts per trial. (e) Mean bout length (n = 5 mice). f, Percent of SPFpPth2 optogenetic stimulation or sham time spent mounting an intact female (all with baseline mounting), unprimed ovariectomized female (ovx; subset of trials without baseline mounting) or ball. g, Same as f, but for number of USVs. h, Locations of ChR2-eYFP expressing cells. Dots on bar plots in (b-g) and colors in plots (h) represent data from individual animals. *p < 0.05, **p < 0.01; ns, not significant. For all figure panels, data are mean ± SEM. Box plot (25th, median and 75th percentiles) and whiskers (min to max). See Table S2 for further details of the statistical analyses.

Back to article page