Extended Data Fig. 7: External validation of PRS models in Taiwan Biobank and other cohorts. | Nature

Extended Data Fig. 7: External validation of PRS models in Taiwan Biobank and other cohorts.

From: Population-specific polygenic risk scores for people of Han Chinese ancestry

Extended Data Fig. 7: External validation of PRS models in Taiwan Biobank and other cohorts.The alternative text for this image may have been generated using AI.

PRS performance is presented as Area Under the receiver operating characteristic Curve (AUC) with 95% confidence inverval in TPMI (orange, TPMI validation set, n = 20,000), Taiwan Biobank (green, n = 88,628), East Asians in UK Biobank (blue, n = 1,572), and East Asians in All of Us (purple, n = 6,895). Circles represent TPMI-derived PRS, and triangles indicate UKB (European)-derived PRS models. Only the estimates with case size > 30 were showed on the figure.

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