Extended Data Fig. 10: Analysis of DNA methylation and RNA expression in the P21 mouse brain.
From: Spatial joint profiling of DNA methylome and transcriptome in tissues
a, UMAP visualization of clusters identified from spatial DNA methylation data (left), spatial RNA transcription data (middle), and integrated DNA and RNA data using WNN analysis (right) for the P21 brain. b, Spatial mapping of CpG (left) and CpA (middle) methylation levels, and RNA expression levels (right) for Satb1 in the P21 brain. c, Spatial mapping of CpG (left) and CpA (middle) methylation levels, and RNA expression levels (right) for Bcl11b in the P21 brain. d, Density plot showing the correlation of gene expression with CpA and CpG methylation in the P21 mouse brain. The plot illustrates the distribution of correlation coefficients, with red indicating CpA methylation and green indicating CpG methylation.
