Extended Data Fig. 8: S-NeuroString for LFP recording in the mouse brain. | Nature

Extended Data Fig. 8: S-NeuroString for LFP recording in the mouse brain.

From: High-density soft bioelectronic fibres for multimodal sensing and stimulation

Extended Data Fig. 8: S-NeuroString for LFP recording in the mouse brain.The alternative text for this image may have been generated using AI.

a, Waterfall plot of the raw LFP data recorded one week after a S-NeuroString was implanted in the hippocampus, band-passed Butterworth filtered between 0.1 – 300 Hz. Colors correspond to the depth of the electrodes where blue is more ventral and purple more dorsal. SWR electrophysiological signatures are apparent and consistent with literature, most notably with the co-occurrence of CA1 and CA3 ripple events as well as an inverse of polarity with depth. b, Spectrogram showing an increase of power centered around 160 Hz. c, Spatial representation of the SWR spectral power at 160 Hz across multiple electrodes revealing stronger engagement in CA1. d, Discrete Fourier transform of channel 7, with a clear peak at 160 Hz indicative of the SWR. e, Firing patterns of individual neurons around SWRs, averaged across 14 events. Multiple neurons show elevated firing rates around a SWR event.

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