Extended Data Fig. 2: Denervation does not offer survival advantage for MYC-driven SCLC. | Nature

Extended Data Fig. 2: Denervation does not offer survival advantage for MYC-driven SCLC.

From: Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

Extended Data Fig. 2: Denervation does not offer survival advantage for MYC-driven SCLC.The alternative text for this image may have been generated using AI.

a, Kaplan–Meier survival curve for sham operated (grey) and denervated (vagotomy; red) animals of RPM-CMV-Cre model (n = 3 sham and n = 3 vagotomy). b, Quantification of tumor burden by percent of lung occupied by tumor for animal cohort in a. c, As in a for RPM-CGRP-Cre model animals (n = 4 sham and n = 4 vagotomy). d, Quantification of tumor burden by percent of lung occupied by tumor for animal cohort in c. Data are mean ± s.e.m. for b, d. Analysis with Log-rank (Mantel-Cox) test for a,c, two-sided unpaired t-test for b,d.

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