Extended Data Fig. 2: Association as well as discordance between RNA and protein expression level in T cells.
From: Proteotoxic stress response drives T cell exhaustion and immune evasion
a, Correlation of RNA and protein expression levels of all detected molecules in Teff and Tex cells 8 days post initial activation. Each dot represents one molecule. A regression line with a shaded 95% confidence interval is shown. (r: Pearson correlation coefficient). b-c, Correlation between RNA levels and protein expression fold changes of molecules across one customer gene set and seven different gene ontologies between Tex and Teff cells (r: Pearson correlation coefficient; n: numbers of proteins/genes mapped to each gene ontology, A regression line with a shaded 95% confidence interval is shown). d, Bar plots of protein and mRNA expression changes of selected transcription factors in Tex vs Teff cells. e, Bar plots of protein and RNA expression changes of molecules belonging to the indicated gene ontologies in Tex vs. Teff cells.
