Extended Data Fig. 3: Assembly graphs of the t(13;14)-bearing GM04890 cell line.
From: The formation and propagation of human Robertsonian chromosomes
Assembly graph of GM04890 integrating PacBio and ONT reads visualized using Bandage. Each chromosome is mostly resolved as a single connected component, with the exception of the acrocentric chromosomes (13, 14, 15, 21 and 22), which are joined by the highly similar rDNA arrays. The graph is colored by Hi-C information used to phase both haplotypes (haplotype 1, red; haplotype 2, blue). The inset shows a portion of the graph involving the acrocentric chromosomes, highlighting the graph node representing the Robertsonian translocation, which connects chromosomes 13 and 14.
