Extended Data Fig. 7: Within-cohort genetic correlation between age at diagnosis stratified autism GWAS and mental health and cognition related phenotypes.
From: Polygenic and developmental profiles of autism differ by age at diagnosis
Genetic correlation between age at autism stratified GWAS in SPARK (meta-analysed from Discovery and Replication cohorts) and iPSYCH and other mental health and cognition related phenotypes. Points represent genetic correlation estimates and whiskers indicate 95% confidence intervals. Green represents the earlier diagnosed autism GWAS (iPSYCH before 9 and SPARK before 6), and purple represents later diagnosed autism GWAS (iPSYCH and SPARK after 10). Asterisk (*) indicates significantly different genetic correlation between the earlier and later diagnosed GWAS (P < 0.05, two-tailed Z test).
