Extended Data Fig. 9: 3D variability analysis.
From: Structural basis for mTORC1 activation on the lysosomal membrane
a, 3DVA processing workflow. b, Particles corresponding to the frames at the two ends of the continuous motion were used for local refinement. Final refinement was done with FSC filtering at 6 Å. c, Close-up view of the ordered loop region in the opposite of ATP binding pocket. The ordered loop is colored red. d, Close-up view of the intermediate and fully active states with Raptor-Rag-Ragulator subcomplex. The membrane-interacting site of Raptor is indicated by red circle.
