Extended Data Fig. 11: Gene expression trajectories across cell types and ages during development.

(a) Heatmap showing the trajectory types of all DE genes, with each column representing a gene and each row corresponding to a subclass. Colors represent different trajectory types, with green representing gene trajectories with increased expression over time, blue representing transiently upregulated gene trajectories, yellow representing transiently downregulated gene trajectories, red representing gene trajectories with decreased expression over time, and grey representing gene trajectories with no change over time. (b-f) Unique gene expression trajectories of individual genes in different subclasses. The trajectories are shown for genes that are expressed in all subclasses (b), genes specific to glutamatergic subclasses (c), GABAergic subclasses (d), glial subclasses (e), or other non-neuronal (NN) subclasses (f). The “Other” label in each panel refers to other subclasses not highlighted in that panel.