Extended Data Fig. 2: ADHD risk across variant categories on the X chromosome.
From: Rare genetic variants confer a high risk of ADHD and implicate neuronal biology
Burden (odds ratio; OR) of class I, class II and rare synonymous variants (SYN) in chromosome X genes stratified by their pLI score. Results are from logistic regression (results in Supplementary Table 8). a, ADHD compared to controls. b, ADHD with no intellectual disability (ID) compared to controls. c, ADHD with ID compared to controls. d, ADHD with ID compared to ADHD without ID. *Indicates nominal significant association P < 0.05, **Indicates significant association after Bonferroni correction correcting for three gene sets (P values less than P = 0.0167 are considered significant).
