Extended Data Fig. 6: Final Local Refinement CryoEM statistics for OrthoRep Affinity Matured TcdB VHH, VHH_TcdB_H2_ortho in complex with TcdB. | Nature

Extended Data Fig. 6: Final Local Refinement CryoEM statistics for OrthoRep Affinity Matured TcdB VHH, VHH_TcdB_H2_ortho in complex with TcdB.

From: Atomically accurate de novo design of antibodies with RFdiffusion

Extended Data Fig. 6: Final Local Refinement CryoEM statistics for OrthoRep Affinity Matured TcdB VHH, VHH_TcdB_H2_ortho in complex with TcdB.The alternative text for this image may have been generated using AI.

Local refinement and masking used to reduce noise from His tag and improve resolution. A) Local Resolution map (Å), calculated using an FSC value of 0.143 viewed along two different angles. B) Global Fourier Shell Correlation plot, Local Refinement. C) Orientational distribution plot. D) Orientational diagnostics data.

Back to article page